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Strong

Coronary Artery Calcium (CAC) Score

Last reviewed 25 August 2026 · Evidence-graded review — see Methodology

A non-contrast CT that quantifies calcified plaque in the coronary arteries and reports it as an Agatston score. The distinction that matters here: it does not estimate risk from risk factors, it images the disease itself. Calcified plaque is a direct, visible marker of atherosclerotic burden that is already present.

Why it grades Strong

Detrano R, Guerci AD, Carr JJ, et al. (MESA) “Coronary Calcium as a Predictor of Coronary Events in Four Racial or Ethnic Groups.” N Engl J Med 2008;358:1336–1345 followed 6,722 adults without known cardiovascular disease and found that a doubling of the calcium score raised the risk of a major coronary event by 15–35% across four racial and ethnic groups, independently of traditional risk factors. The 2018 ACC/AHA cholesterol guideline now incorporates CAC scoring as a formal decision aid: in intermediate-risk patients a score of zero can support deferring statin therapy, while a high score supports intensifying it. Arguably the best-evidenced “extra” test on this site.

Detrano R, et al. N Engl J Med. 2008. PubMed: PMID 18367736 · Full cost breakdown & who it's for →

FrequencyOnce around age 40–50 (intermediate risk); repeat testing is not usually indicated within 5 years if score is 0
Cost (SGD)S$300–550
Appropriate forAdults at intermediate calculated cardiovascular risk, to guide the statin decision. Not useful in very-low or very-high risk adults where the decision is already clear, and not recommended under ~age 40 without strong risk factors (low pre-test probability, some radiation exposure)

What you would actually pay

Healthier SG
Not subsidised
MediSave
Not among the screenings named for outpatient claims

Source: Healthier SG Screening (HealthHub) and MediSave outpatient care (Ministry of Health). Absence from either list is not a statement that the test is discouraged — only that no subsidy or claim applies. Gross prices compared.

What it costs when it is wrong

Basis
No published harm criterion found
Severity
Not documented

No published harm criterion found for this test.

An empty finding, not a clean bill of health: this means nothing documented was found for this test. It is not a claim that the test is safe.

Screening harm is not only a laboratory question: the committee’s own criteria advise against a test when “the screening test, or follow-up tests arising from a positive screen, are associated with significant medical risks”. Sources on overdiagnosis → · How this is graded.

Singapore pricing. We have a full price breakdown for this test, using checked 2026 figures from named providers — read the price guide →

FAQ

Is the Coronary Artery Calcium (CAC) Score worth doing in Singapore?

Coronary Artery Calcium (CAC) Score carries a strong evidence grade for screening adults without symptoms. It typically costs S$300–550 in Singapore. Most appropriate for adults at intermediate calculated cardiovascular risk, to guide the statin decision. Not useful in very-low or very-high risk adults where the decision is already clear, and not recommended under ~age 40 without strong risk factors (low pre-test probability, some radiation exposure). The usual schedule: once around age 40–50 (intermediate risk); repeat testing is not usually indicated within 5 years if score is 0.